A REVIEW OF NAD+ AND ITS ROLE IN MITOCHONDRIAL FUNCTION

Next, we dealt with cells with unique concentrations of NAD+. When added for 24 h at 80 µM in HeLa and 400 µM in U2OS cells, NAD+ impaired the incorporation of EdU (Fig. 2a and Extended Details Fig. 1k,l). Additionally, sixteen µM of NAD+ was sufficient to lessen fork velocity by ~40% in HeLa cells with no influencing the entire amount o